| Judul | Antibody Titer Has Positive Predictive Value for Vaccine Protection against Challenge with Natural Antigenic-Drift Variants of H5N1 High-Pathog enicity Avian Influenza Viruses from Indonesia / David E. Swayne; David L. Suarez; Erica Spackman; Samadhan Jadhao; Gwenaelle Dauphin; Mia Kim-Torchetti; James McGrane; John Weaver; Peter Daniels; Frank Wong; Paul Selleck; Agus Wiyono; Risa Indriani; Yuni Yupiana; Elly Sawitri Siregar; Teguh Prajitno; D |
| Pengarang | David L. Suarez Erica Spackman Samadhan Jadhao Gwenaelle Dauphin Mia Kim-Torchetti James McGrane John Weaver Peter Daniels Frank Wong Paul Selleck Agus Wiyono Risa Indriani Yuni Yupiana Elly Sawitri Siregar Teguh Prajitno D |
| EDISI | Journal of Virology |
| Penerbitan | 2015 |
| Deskripsi Fisik | Vol. 89 (7), p.3746-3762 |
| Subjek | Avian influenza, HPAI, H5N1 |
| Abstrak | Vaccines are used in integrated control strategies to protect poultry against H5N1 high-pathogenicity avian influenza (HPAI). H5N1 HPAI was first reported in Indonesia in 2003, and vaccination was initiated in 2004, but reports of vaccine failures began to emerge in mid-2005. This study investigated the role of Indonesian licensed vaccines, specific vaccine seed strains, and emerg- ing variant field viruses as causes of vaccine failures. Eleven of 14 licensed vaccines contained the manufacturer’s listed vaccine seed strains, but 3 vaccines contained a seed strain different from that listed on the label. Vaccines containing A/turkey/Wiscon- sin/1968 (WI/68), A/chicken/Mexico/28159-232/1994 (Mex/94), and A/turkey/England/N28/1973 seed strains had high serologi- cal potency in chickens (geometric mean hemagglutination inhibition [HI] titers, >1:169), but vaccines containing strain A/chicken/Guangdong/1/1996 generated by reverse genetics (rg; rgGD/96), A/chicken/Legok/2003 (Legok/03), A |
| Bentuk Karya | Tidak ada kode yang sesuai |
| Target Pembaca | Tidak ada kode yang sesuai |
| Lokasi Akses Online | http://dx.doi.org/10.1128/JVI.00025-15 |
| No Barcode | No. Panggil | Akses | Lokasi | Ketersediaan |
|---|---|---|---|---|
| ARTVET2079 | ARTVET2079 | Dapat dipinjam | Perpustakaan Balai Besar Pengujian Standar Instrumen Veteriner - Koleksi Agris | Tersedia |
| Tag | Ind1 | Ind2 | Isi |
| 001 | INLIS000000000017806 | ||
| 005 | 20210804090945 | ||
| 008 | 210804################|##########|#|## | ||
| 035 | # | # | $a 0010-0721002338 |
| 082 | # | # | $a ARTVET2079 |
| 084 | # | # | $a ARTVET2079 |
| 245 | # | # | $a Antibody Titer Has Positive Predictive Value for Vaccine Protection against Challenge with Natural Antigenic-Drift Variants of H5N1 High-Pathog enicity Avian Influenza Viruses from Indonesia /$c David E. Swayne; David L. Suarez; Erica Spackman; Samadhan Jadhao; Gwenaelle Dauphin; Mia Kim-Torchetti; James McGrane; John Weaver; Peter Daniels; Frank Wong; Paul Selleck; Agus Wiyono; Risa Indriani; Yuni Yupiana; Elly Sawitri Siregar; Teguh Prajitno; D |
| 250 | # | # | $a Journal of Virology |
| 260 | # | # | ,$c 2015 |
| 300 | # | # | $a Vol. 89 (7), p.3746-3762 |
| 520 | # | # | $a Vaccines are used in integrated control strategies to protect poultry against H5N1 high-pathogenicity avian influenza (HPAI). H5N1 HPAI was first reported in Indonesia in 2003, and vaccination was initiated in 2004, but reports of vaccine failures began to emerge in mid-2005. This study investigated the role of Indonesian licensed vaccines, specific vaccine seed strains, and emerg- ing variant field viruses as causes of vaccine failures. Eleven of 14 licensed vaccines contained the manufacturer’s listed vaccine seed strains, but 3 vaccines contained a seed strain different from that listed on the label. Vaccines containing A/turkey/Wiscon- sin/1968 (WI/68), A/chicken/Mexico/28159-232/1994 (Mex/94), and A/turkey/England/N28/1973 seed strains had high serologi- cal potency in chickens (geometric mean hemagglutination inhibition [HI] titers, >1:169), but vaccines containing strain A/chicken/Guangdong/1/1996 generated by reverse genetics (rg; rgGD/96), A/chicken/Legok/2003 (Legok/03), A/chicken/Viet- nam/C57/2004 generated by rg (rgVN/04), or A/chicken/Legok/2003 generated by rg (rgLegok/03) had lower serological potency (geometric mean HI titers, <1:95). In challenge studies, chickens immunized with any of the H5 avian influenza vaccines were protected against A/chicken/West Java/SMI-HAMD/2006 (SMI-HAMD/06) and were partially protected against A/chicken/Pap- ua/TA5/2006 (Papua/06) but were not protected against A/chicken/West Java/PWT-WIJ/2006 (PWT/06). Experimental inacti- vated vaccines made with PWT/06 HPAI virus or rg-generated PWT/06 low-pathogenicity avian influenza (LPAI) virus seed strains protected chickens from lethal challenge, as did a combination of a commercially available live fowl poxvirus vaccine ex- pressing the H5 influenza virus gene and inactivated Legok/03 vaccine. These studies indicate that antigenic variants did emerge in Indonesia following widespread H5 avian influenza vaccine usage, and efficacious inactivated vaccines can be developed using antigenic variant wild-type viruses or rg-generated LPAI virus seed strains containing the hemagglutinin and neuraminidase genes of wild-type viruses. |
| 650 | # | 4 | $a Avian influenza, HPAI, H5N1 |
| 700 | # | $a Agus Wiyono | |
| 700 | # | $a D | |
| 700 | # | $a David L. Suarez | |
| 700 | # | $a Elly Sawitri Siregar | |
| 700 | # | $a Erica Spackman | |
| 700 | # | $a Frank Wong | |
| 700 | # | $a Gwenaelle Dauphin | |
| 700 | # | $a James McGrane | |
| 700 | # | $a John Weaver | |
| 700 | # | $a Mia Kim-Torchetti | |
| 700 | # | $a Paul Selleck | |
| 700 | # | $a Peter Daniels | |
| 700 | # | $a Risa Indriani | |
| 700 | # | $a Samadhan Jadhao | |
| 700 | # | $a Teguh Prajitno | |
| 700 | # | $a Yuni Yupiana | |
| 856 | # | # | $a http://dx.doi.org/10.1128/JVI.00025-15 |
| 990 | # | # | $a ARTVET2079 |
| No | Nama File | Nama File Format Flash | Format File | Action |
| 1 | ARTVET2079.pdf | ARTVET2079 | Baca Online |
Content Unduh katalog
Karya Terkait :