| Judul | Vaccine Efficacy on the Novel Reassortant H9N2 Virus in Indonesia / Dharmayanti, Ni Luh Putu Indi ; Indriani, Risa Nurjanah, Diana (Balai Besar Penelitian Veteriner) |
| Pengarang | Indriani, Risa Nurjanah, Diana (Balai Besar Penelitian Veteriner) |
| EDISI | Vaccines |
| Penerbitan | 2020 |
| Deskripsi Fisik | Vol. 8, 449. 2020 |
| Subjek | avian influenza; reassortant; inactivated; vaccine; pathogenicity; efficacy |
| Abstrak | Vaccination is one of the leading methods of controlling the spread of the Avian Influenza (AI) viruses in Indonesia. The variety of circulating viruses and their ability to mutate must be followed by updating the vaccine master seed used in the field. In this study, we identified the reassortant H9N2 viruses in chicken farms that showed significant problems in decreased egg production with high mortality. The reassortant H9N2 viruses derived the PB2 gene from the H5N1 virus. The pathogenicity test results of the reassortant virus showed various clinical signs of illness, a high mortality rate (10%), and decreased egg production down to 63.12% at two weeks post-infection. In a vaccine ecacy test, the vaccinated groups showed minimally decreased egg production that started to increase to more than 80% at 4–7 weeks post-challenge. Our study showed that inactivated bivalent and monovalent reassortant H9N2 vaccines can induce antibody response, reducing the mortality and virus shedding caused by reasso |
| Bentuk Karya | Tidak ada kode yang sesuai |
| Target Pembaca | Tidak ada kode yang sesuai |
| Lokasi Akses Online | doi:10.3390/vaccines8030449 |
| No Barcode | No. Panggil | Akses | Lokasi | Ketersediaan |
|---|---|---|---|---|
| ARTVET2269 | ARTVET2269 | Dapat dipinjam | Perpustakaan Balai Besar Pengujian Standar Instrumen Veteriner - Koleksi Agris | Tersedia |
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| 001 | INLIS000000000017637 | ||
| 005 | 20221206094825 | ||
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| 084 | # | # | $a ARTVET2269 |
| 245 | # | # | $a Vaccine Efficacy on the Novel Reassortant H9N2 Virus in Indonesia /$c Dharmayanti, Ni Luh Putu Indi ; Indriani, Risa Nurjanah, Diana (Balai Besar Penelitian Veteriner) |
| 250 | # | # | $a Vaccines |
| 260 | # | # | ,$c 2020 |
| 300 | # | # | $a Vol. 8, 449. 2020 |
| 520 | # | # | $a Vaccination is one of the leading methods of controlling the spread of the Avian Influenza (AI) viruses in Indonesia. The variety of circulating viruses and their ability to mutate must be followed by updating the vaccine master seed used in the field. In this study, we identified the reassortant H9N2 viruses in chicken farms that showed significant problems in decreased egg production with high mortality. The reassortant H9N2 viruses derived the PB2 gene from the H5N1 virus. The pathogenicity test results of the reassortant virus showed various clinical signs of illness, a high mortality rate (10%), and decreased egg production down to 63.12% at two weeks post-infection. In a vaccine ecacy test, the vaccinated groups showed minimally decreased egg production that started to increase to more than 80% at 4–7 weeks post-challenge. Our study showed that inactivated bivalent and monovalent reassortant H9N2 vaccines can induce antibody response, reducing the mortality and virus shedding caused by reassortant H9N2 virus infection. The reassortant H9N2 virus is a threat that requires vigilance in poultry farms and the industry. The vaccines used in this study can be one of the options for control or prevention measures on farms infected with the reassortant H9N2 viruses. |
| 650 | # | 4 | $a avian influenza; reassortant; inactivated; vaccine; pathogenicity; efficacy |
| 700 | # | $a Indriani, Risa Nurjanah, Diana (Balai Besar Penelitian Veteriner) | |
| 856 | # | # | $a doi:10.3390/vaccines8030449 |
| 990 | # | # | $a ARTVET2269 |
| No | Nama File | Nama File Format Flash | Format File | Action |
| 1 | ARTVET2269.pdf | ARTVET2269 | Baca Online |
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