01611     2200157   4500001002100000005001500021035002000036008004100056082001100097090001100108100001600119700002100135245017500156260000900331500111300340INLIS00000000000217120240219092235  a0010-0521002171240219                |          |        a--/636  a--/6360 aUTOJO, R.P.0 aGirindra, I.G.N.1 aBovine tuberculosis treatment by isonicotinic acid hydrazide (INH). / UTOJO, R.P. ; GIRINDRA, I.G.N. (CENTRAL Institute for Animal Health Bogor, Indonesia) /cUTOJO, R.P.  c1962  aBOGOR VETERINARY BULLETIN .-- No.2 p.19-36.-- ABSTRAK : Proceding investigations surveyed the preventive action of isonicotinic acid hydrazide upon tuberculosis infection and concluded unanimously that the chemical in question is strongly active. In this examination it is attempted to make a survey upon the activity of isoniazide if applied simultaneously with the (artificial) infection, or after infection took place. The survey has been made on guinea pigs as well as on calves, which after artificial infection were submitted to a treatment scheduled according to the extant of intervals between infection and initial drug application. In this test has been proved the valuability of action of INH on guinea pigs and calves; they were protected against spreading of tuberculose processes in case the therapy began ten days after intramuscular infection and continues for at least two months so far it cencerns guineapigs and 45 days after intravenous infection and continues for at least 6 months so far it cencerns bovines. Similar investigation as to the more natural infection has not been done yet.