DYAH HARYUNINGTYAS text Balai Besar Penelitian Veteriner Seminar Nasional Teknologi Peternakan dan Veteriner 2011

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8 Scabies is a zoonotic parasitic disease caused by Sarcoptes scabiei mite. The mite commonly infests skin of goat. Control scabies using synthetic drugs have limitation because of the expensive price, negative effect to environment, emerging problem of drug resistance and also unavailability in the rural area. Therefore, it is needed to develop a botanical acariside research as an alternative drug which are cheap and accescible for farmer. The aim of the invitro study was to investigate the potency of bengkuang Pachyrhizus erosus seeds against S. scabiei collected from goat skin. The extraction was performed using acetone and water. Two hundred and seventy mites were used in this study and divided into two groups e.g. water (1, 2.5, and 5% concentration), and acetone extracts group (2.5; % and 10%). Cypermetrin 25% was used as positive control. Six extract solutions were tested to mite mortality (LT50 and LT95) in incubation chamber and observed every hour for 6 hours. The mortality data analysed using probit analisis with 95% significant level. The result demonstrated that active coumpound of bengkuang (Pachyrhizus erosus) seeds (rotenone) had effectively contact toxic property for S. scabiei at 5% concentration both in water and acetone extract. Water extracts have LC50 and LC95 for 8.5 and 0.8 and acetone extract for 2,3 and 11.3 respectively on 5 hours. The lethal concentration of acetone extract were lower than water extract on 5% concentration e.g. 1.8 hours (LT50); 4.8 hours (LT95) and 2.5 hours (LT50); 5 hours (LT95) respectively. Five percent of water extracts Pachyrhizus erosus seed concentration was applicable for farmer in the rural area since it was cheap and practical and also effective to kill mite. DYAH HARYUNINGTYAS BIJI BENGKUANG ARTVET2448 ARTVET2448 250204 20250204111749 INLIS000000000019149 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)