02491     2200217   4500001002100000005001500021035002000036007000300056008003900059082001500098084001500113100002300128245016800151260009900319300000600418650002000424700001400444700002100458520177900479990001502258INLIS00000000001914920250204111749  a0010-0924000228ta250204                |          | |    aARTVET2448  aARTVET24480 aDYAH HARYUNINGTYAS1 aEFEKTIVITAS  EKSTRAK  BIJI  BENGKUANG  (Pachyrhizus  erosus) DENGAN PELARUT AIR DAN ASETON TERHADAP  TUNGAU Sarcoptes scabiei SECARA IN VITRO /cDYAH HARYUNINGTYAS  aBalai Besar Penelitian Veteriner :bSeminar Nasional Teknologi Peternakan dan Veteriner,c2011  a8 4aBIJI  BENGKUANG0 aYUNINGSIH0 aS.E. ESTUNINGSIH  aScabies is a zoonotic parasitic disease caused by Sarcoptes scabiei mite. The mite commonly infests skin 
of goat. Control scabies using synthetic drugs have limitation because of the expensive price, negative effect 
to environment, emerging problem of drug resistance and also unavailability in the rural area. Therefore, it is 
needed to develop a botanical acariside research as an alternative drug which are cheap and accescible for 
farmer. The aim of the invitro study was to investigate the potency of bengkuang Pachyrhizus erosus seeds 
against S. scabiei collected from goat skin. The extraction was performed using acetone and water. Two 
hundred and seventy mites were used in this study and divided into two groups e.g. water (1, 2.5, and 5% 
concentration), and acetone extracts group (2.5; % and 10%). Cypermetrin 25% was used as positive control. 
Six extract solutions were tested to mite mortality (LT50 and LT95) in incubation chamber and observed every 
hour for 6 hours. The mortality data analysed using probit analisis with 95% significant level. The result 
demonstrated that active coumpound of bengkuang (Pachyrhizus erosus) seeds (rotenone) had effectively 
contact toxic property for S. scabiei at 5% concentration both in water and acetone extract. Water extracts 
have LC50 and LC95 for 8.5 and 0.8 and acetone extract for 2,3 and 11.3 respectively on 5 hours. The lethal 
concentration of acetone extract were lower than water extract on 5% concentration e.g. 1.8 hours (LT50); 4.8 
hours (LT95) and 2.5 hours (LT50); 5 hours (LT95) respectively. Five percent of water extracts Pachyrhizus 
erosus seed concentration was applicable for farmer in the rural area since it was cheap and practical and also 
effective to kill mite.  aARTVET2448