RISA INDRIANI text Institute Centre Research of Veterinary International Conference on Livestock Production and Veterinary Technology 2012

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5 Highly Pathogenic Avian Influenza (HPAI) subtype H5N1 has been in Indonesia since the middle of 2003. Vaccination of chickens has become a routine practice in the countries of Asia (including Indonesia) where HPAI is endemic. This is especially conducted for layer and breeder farms, but the broilers are often left unvaccinated. To observe the innate immune antibodies against AI subtype H5, which derived from hens in young broilers, this experiment was conducted on commercial broiler farms in sector 3. Seventeen farms which located in the district of Sukabumi and Cianjur were chosen. Twenty serum samples were collected randomly from each farm by random at the time of broiler day old chicks (DOC), two weeks of age and at around four to five weeks of age or market ready. Serum samples were tested by using haemagglutination inhibition (HI) against three antigen isolates of AI subtype H5N1 and one antigen of subtype AI H5N2. Data from HI tests were analyzed as the geometric mean titre (GMT) and negative titre (< 16) was regarded as 4 for the calculation of GMT. Results of analysis of serum samples showed that DOC of broiler chickens had maternal antibody titre of AI subtype H5 were ? 16, then at 2 weeks of age the maternal antibody titre subtype H5 were < 16 and at the time market ready or at 4 – 5 weeks of age the maternal antibody titre AI subtype H5 has reached 0. It is concluded that maternal antibody against AI subtype H5 in broiler is no longer providing protection, and it is possible that broiler chickens could be infected with AI virus in the field. RISA INDRIANI AVIAN INFLUENZA SUBTYPE H5 ARTVET1814 ARTVET1814 240911 20240911082921 INLIS000000000019146 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)