FAIDAH RACHMAWATI text Balai Besar Penelitian Veteriner WARTAZOA 2010 Vol. 20 No. 4

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8 Mycoplasma synoviae (MS) infection of chicken is the most costly disease against poultry industries. Generally, MS infection is preceded by subclinical condition where MS organisms are located in the respiratory tract. In the stadium of septicemia, the infection can become acute to chronic, and cause swollen of the hock and toe joints. The swollen joints contain accumulation of exudates in the synovial membranes and tendon sheath. The clinical symptoms appeared as difficulty to move resulting from swollen of the joints, reduced appetite, depression, and weight loss and followed by death. Up to now, MS infection has spread worldwide including Indonesia, and it is stated as a Notifiable disease by OIE, means that the disease should be reported to the government if the outbreak occurs in the chicken farm. The spread of the disease can occur through horizontal and vertical transmissions. Diagnosis can be made based on clinical symptoms, serology examination, gross pathological lesions and isolation and identification of MS organisms. Macrolide antibiotics can be used for treating MS infection although the result is not satisfied. Biosecurity, sanitation and vaccination programs can be used for the prevention and control of the disease. These efforts are important to prevent the incoming and spreading of MS organisms into the farm. Vaccination is the best choice for prevention of the disease, and it is hope that the routine vaccination can be used as a tool for eradication program of MS infection in the future. FAIDAH RACHMAWATI INFEKSI Mycoplasma synoviae ARTVET1659 ARTVET1659 240910 20240910125124 INLIS000000000019105 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)