02104     2200205   4500001002100000005001500021035002000036007000300056008003900059082001500098084001500113100002200128245006300150250001800213260005600231300000600287650003200293700001300325520156000338INLIS00000000001910520240910125124  a0010-0924000184ta240910                |          | |    aARTVET1659  aARTVET16590 aFAIDAH RACHMAWATI1 aINFEKSI Mycoplasma synoviae PADA AYAM /cFAIDAH RACHMAWATI  aVol. 20 No. 4  aBalai Besar Penelitian Veteriner :bWARTAZOA,c2010  a8 4aINFEKSI Mycoplasma synoviae0 aSOERIPTO  aMycoplasma synoviae (MS) infection of chicken is the most costly disease against poultry industries. Generally, MS 
infection is preceded by subclinical condition where MS organisms are located in the respiratory tract. In the stadium of 
septicemia, the infection can become acute to chronic, and cause swollen of the hock and toe joints. The swollen joints contain 
accumulation of exudates in the synovial membranes and tendon sheath. The clinical symptoms appeared as difficulty to move 
resulting from swollen of the joints, reduced appetite, depression, and weight loss and followed by death. Up to now, MS 
infection has spread worldwide including Indonesia, and it is stated as a Notifiable disease by OIE, means that the disease should 
be reported to the government if the outbreak occurs in the chicken farm. The spread of the disease can occur through horizontal 
and vertical transmissions. Diagnosis can be made based on clinical symptoms, serology examination, gross pathological lesions 
and isolation and identification of MS organisms. Macrolide antibiotics can be used for treating MS infection although the result 
is not satisfied. Biosecurity, sanitation and vaccination programs can be used for the prevention and control of the disease. These 
efforts are important to prevent the incoming and spreading of MS organisms into the farm. Vaccination is the best choice for 
prevention of the disease, and it is hope that the routine vaccination can be used as a tool for eradication program of MS infection 
in the future.