EFEK IMUNOSUPRESI PADA AYAM YANG MENETAS DARI TELUR BEREMBRIO YANG DIINOKULASI DENGAN AFLATOKSIN R. WIDIASTUTI text Balai Penelitian Veteriner Prosiding Temu Ilmiah Nasional Bidang Veteriner 1996

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6 This preliminary research was conducted as attempts to investigate a possible immunosupressive effect on chicks hatched from anbryonated eggs contaminated with aflatoxin (AFBI). In the present study, 5-day-old chicken embryos were innoculated wa tbe air sac, by 10 Id solution of AFBI (dissolved in 5% ethanol) at concentrations of 1 ppm, 2 ppm and 4 ppm. Whereas the control were innoculated by 10 pl of 5% ethanol. Three chicks hatched both from treated eggs and control were vaccinated twice at 4 and 14 days of age by Newcastle Disease (ND) virus, and therefore those chicks were assignated as group 1 (1 ppm * ND), group 11(2 ppm + ND), group I11(4 ppm + ND) dan group IV (Control + ND). In this study 3 chicks from control group but without vaccination, group V (Control - ND) was also chosen. The observation of antibody titres was done every week during experiMentation. The remits showed group IV (Control + ND) gave the highest antibody titres compared to others. Meanwhile, chicks batched from eggs with AFBI immolation gave lower antibody titres which decreased as the AFBI increasing. From this study, it an be concluded that AFIll inoculated to the embryonated eggs showed the inunuriesuppressive effect to those aticks hatched. R. WIDIASTUTI EFEK IMUNOSUPRESI PADA AYAM ARTVET824 ARTVET824 240906 20240906013250 INLIS000000000018995 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)