01898     2200205   4500001002100000005001500021035002000036007000300056008003900059082001400098084001400112100001800126245013900144260008900283300000600372650003200378700001300410700001300423520125600436INLIS00000000001899520240906013250  a0010-0924000074ta240906                |          | |    aARTVET824  aARTVET8240 aR. WIDIASTUTI1 aSTUDI PENDAHULUAN :bEFEK IMUNOSUPRESI PADA AYAM YANG MENETAS DARI TELUR BEREMBRIO YANG DIINOKULASI DENGAN AFLATOKSIN /cR. WIDIASTUTI  aBalai Penelitian Veteriner :bProsiding Temu Ilmiah Nasional Bidang Veteriner,c1996  a6 4aEFEK IMUNOSUPRESI PADA AYAM0 aS. BAHRI0 aDARMINTO  aThis preliminary research was conducted as attempts to investigate a possible immunosupressive effect on chicks hatched from
anbryonated eggs contaminated with aflatoxin (AFBI). In the present study, 5-day-old chicken embryos were innoculated wa tbe air
sac, by 10 Id solution of AFBI (dissolved in 5% ethanol) at concentrations of 1 ppm, 2 ppm and 4 ppm. Whereas the control were
innoculated by 10 pl of 5% ethanol. Three chicks hatched both from treated eggs and control were vaccinated twice at 4 and 14 days
of age by Newcastle Disease (ND) virus, and therefore those chicks were assignated as group 1 (1 ppm * ND), group 11(2 ppm +
ND), group I11(4 ppm + ND) dan group IV (Control + ND). In this study 3 chicks from control group but without vaccination, group
V (Control - ND) was also chosen. The observation of antibody titres was done every week during experiMentation. The remits
showed group IV (Control + ND) gave the highest antibody titres compared to others. Meanwhile, chicks batched from eggs with
AFBI immolation gave lower antibody titres which decreased as the AFBI increasing. From this study, it an be concluded that
AFIll inoculated to the embryonated eggs showed the inunuriesuppressive effect to those aticks hatched.