02466     2200433   4500001002100000005001500021035002000036007000300056008003900059084001500098100002500113245014900138250003800287260000900325300001200334650001500346650000900361650002900370650002300399650002900422700002000451700002100471700001800492700002600510700002200536700002100558700003000579700002200609700002500631700002100656700002400677700002200701700002100723700002100744700002000765520120100785856003101986020001502017INLIS00000000001875420240207031859  a0010-0224000004ta240207                |          | |    aARTVET23800 aBlacksell, Stuart D.1 aThe Biosafety Research Road Map :bThe Search for Evidence to Support Practices in the Laboratory—Mpox/Monkeypox Virus /cBlacksell, Stuart D.  aApplied Biosafety, Vol, 28, No, 3  c2023  a152-161 4ampox virus 4ampox 4apathogen characteristics 4abiosafety evidence 4abiosafety knowledge gaps0 aDhawan, Sandhya0 aKusumoto, Marina0 aLe, Kim Khanh0 aSummermatter, Kathrin0 aO’Keefe, Joseph0 aKozlovac, Joseph0 aMuhairi, Salama Suhail Al0 aSendow, Indrawati0 aScheel, Christina M.0 aAhumibe, Anthony0 aMasuku, Zibusiso M.0 aBennett, Allan M.0 aKojima, Kazunobu0 aHarper, David R.0 aHamilton, Keith  aIntroduction: The virus formerly known as monkeypox virus, now called mpoxv, belongs to the Orthopox-
virus genus and can cause mpox disease through both animal-to-human and human-to-human transmis-
sion. The unexpected spread of mpoxv among humans has prompted the World Health Organization
(WHO) to declare a Public Health Emergency of International Concern (PHEIC).
Methods: We conducted a literature search to identify the gaps in biosafety, focusing on ?ve main areas: how the
infection enters the body and spreads, how much of the virus is needed to cause infection, infections acquired in
the lab, accidental release of the virus, and strategies for disinfecting and decontaminating the area.
Discussion: The recent PHEIC has shown that there are gaps in our knowledge of biosafety when it comes
to mpoxv. We need to better understand where this virus might be found, how much of it can spread from
person-to-person, what are the effective control measures, and how to safely clean up contaminated areas.
By gathering more biosafety evidence, we can make better decisions to protect people from this zoonotic
agent, which has recently become more common in the human population.  aDOI: 10.1089/apb.2022.0045  aARTVET2380