01765     2200217   4500001002100000005001500021035002000036245024200056700002000298700002300318700002600341250004500367260000900412300002500421084001500446082001500461008003900476650004800515520096900563990001501532INLIS00000000001765920211012081331  a0010-0721002191  aGenetic characterization of H5N1 avian influenza viruses isolated from pet bird and chickens from live bird market in Bali and Bekasi (Indonesia), 2011 /cDharmayanti, NLP Indi ; Rahmawati, Atik; Hewajuli, Dyah Ayu; Indrian, Risa (IRCVS)  aRahmawati, Atik  aHewajuli, Dyah Ayu  aIndrian, Risa (IRCVS)  aAfrican Journal of Microbiology Research  c2014  aVol.8 (3), p.244-251  aARTVET2005  aARTVET2005211012                |          | |   4aGenetic character, H5N1, birds, LBM, source  aIndonesia has endemic status of H5N1 and the largest number of human cases of H5N1. Sources of
human infections include mostly intensive contact with H5N1 virus or the environment contaminated by
this virus. This study shows that feaces from pet bird victims and chickens were sold in live bird market
(LBM) suspected to be the source of infection for human H5N1 in Bali and Bekasi in 2011. This study
focused on the virus’ genetic character that originated from these areas, especially HA1, M, NS1 and
PB2 genes. The results show that Bali and Bekasi viruses have similar genetic characters with human
H5N1 viruses in Indonesia. The viruses have multiple basic amino acids in hemagglutinin that showed
highly pathogenic, specific motif amino acid in the Matrix protein and ESEV motif on NS1. The viruses
have no mutations in PB2 gene. The findings support that most cases of human H5N1 infection are as a
result of exposure of birds to H5N1 virus.  aARTVET2005