text 2011 Prosiding The Joint Meeting of Conference and Congres Asian Society of Veterinary Pathology 2011 and the 10th Scientific Symposium of Indonesian Society of Veterinary Pathlogy (ISVP) 2011 22-24 November 2011, Bogor-Indonesia, p.96-97 Bovine Spongiform Encephalopathy (BSE) is a fatal, degenerative and progressive disease affecting neurological system of cattle, due to proteinaceous infectious or prion (PrP). The disease was firstly reported in Brirain in 1985 and confirmed microscopically in 1986 (WELLS et al., 1987). Since 1986 more than 25.000 cattle were infected and it spread to 23 countries by the end of 2004. The dieasease was affecting adult cattle because its long incubation period (1.5-8 years). It was stongly assumed that the transmission of the disease is by cnsumption of contaminated meat bone meals (MBM) (BRADLEY and WILESMITH, 1993). Damayanti,Rini (Indonesian Research Center for Veterinary Science) BSE, prion protein (PrP), immunohistochemistry, feedlot cattle ARTVET2002 ARTVET2002 211012 20211012090344 INLIS000000000017656 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)