na INLIS000000000017656 20211012090344 0010-0721002188 The Application Of Immunohistochemistry To Detect Prion Protein (prp) of Bovine Sponggiform Encephalopathy (BSE) in Feedlot Cattle To Anticipate BSE Emergence In Indonesia / Damayanti,Rini (Indonesian Research Center for Veterinary Science) Prosiding The Joint Meeting of Conference and Congres Asian Society of Veterinary Pathology 2011 and the 10th Scientific Symposium of Indonesian Society of Veterinary Pathlogy (ISVP) 2011 2011 22-24 November 2011, Bogor-Indonesia, p.96-97 ARTVET2002 ARTVET2002 211012 | | | BSE, prion protein (PrP), immunohistochemistry, feedlot cattle Bovine Spongiform Encephalopathy (BSE) is a fatal, degenerative and progressive disease affecting neurological system of cattle, due to proteinaceous infectious or prion (PrP). The disease was firstly reported in Brirain in 1985 and confirmed microscopically in 1986 (WELLS et al., 1987). Since 1986 more than 25.000 cattle were infected and it spread to 23 countries by the end of 2004. The dieasease was affecting adult cattle because its long incubation period (1.5-8 years). It was stongly assumed that the transmission of the disease is by cnsumption of contaminated meat bone meals (MBM) (BRADLEY and WILESMITH, 1993). ARTVET2002