01531     2200181   4500001002100000005001500021035002000036245024600056250019200302260000900494300005000503084001500553082001500568008003900583650006700622520064500689990001501334INLIS00000000001765620211012090344  a0010-0721002188  aThe Application Of Immunohistochemistry To Detect Prion Protein (prp) of Bovine Sponggiform Encephalopathy (BSE) in Feedlot Cattle To Anticipate BSE Emergence In Indonesia /cDamayanti,Rini (Indonesian Research Center for Veterinary Science)  aProsiding The Joint Meeting of Conference and Congres Asian Society of Veterinary Pathology 2011 and the 10th Scientific Symposium of Indonesian Society of Veterinary Pathlogy (ISVP) 2011  c2011  a22-24 November 2011, Bogor-Indonesia, p.96-97  aARTVET2002  aARTVET2002211012                |          | |   4aBSE, prion protein (PrP), immunohistochemistry, feedlot cattle  aBovine Spongiform Encephalopathy 
(BSE) is a fatal, degenerative and progressive
disease affecting neurological system of
cattle, due to proteinaceous infectious or
prion (PrP). The disease was firstly reported
in Brirain in 1985 and confirmed
microscopically in 1986 (WELLS et al.,
1987). Since 1986 more than 25.000 cattle
were infected and it spread to 23 countries by
the end of 2004. The dieasease was affecting
adult cattle because its long incubation period
(1.5-8 years). It was stongly assumed that
the transmission of the disease is by
cnsumption of contaminated meat bone meals
(MBM) (BRADLEY and WILESMITH,
1993).  aARTVET2002