text 2005 WARTAZOA. Vol .15(3) p. 111-118. (2005). Japanese encephalitis (JE) is a zoonotic viral disease which causes encephalitis in children (5-9 years old) . The disease is transmitted by mosquitoes . The presence of JE virus, vector and reservoir host in Indonesia, will increase the concern of the possibility of JE outbreak in Indonesia . JE infection in human was reported by clinical and serological findings. Recently, JE case in Bali was declared as hyperendemic (usually sporadic) . In animals, JE infection has been confirmed by serology and viral isolation, while JE vector had been found in different species of mosquitoes by successful viral isolation from those mosquitoes . The prevention and control of JE are conducted by socialization about JE to the society, by cutting the JE transmission cycle (virus, vector and host), including pig farm relocation . The development of regional laboratories (facilities and human resources) to diagnose JE and the establishment BSL of 3 laboratory in the central laboratory institute to isolate the JE virus and to conduct further JE research on the role of animal in transmitting JE to human, must be conducted . / Japanese enecephalitis (JE) adalah penyakit viral yang bersifat zoonosis dan menyebabkan peradangan otak pada manusia usia muda (5-9 tahun) yang ditularkan melalui vektor nyamuk. Keberadaan virus penyebab JE, vektor dan hewan reservoar di berbagai wilayah Indonesia, menyebabkan perlunya kewaspadaan terhadap kemungkinan mewabahnya penyakit ini. Keberasaan JE pada manusia di Indonesia telah diungkapkan berdasarkan gejala klinis dan pemeriksaan serologis, dan perkembangan terakhir kejadian JE di Bali telah menjadi hiperendemik (yang biasanya sporadik). Pada hewan kejadian JE hanya ditemukan berdasarkan serologis dan isolasi virus penyebabnya, sedangkan keberadaan vektor berupa nyamuk telah ditemukan berbagai spesies nyamuk yang potensial menularkan JE karena virus penyebab JE berhasil diisolasi dari nyamuk. Sendow, Indrawati; Bahri, Sjamsul(Balai Penelitian Veteriner, Bogor Indonesia). ARTVET1134 ARTVET1134 210727 20210727081536 INLIS000000000016602 Converted from MARCXML to MODS version 3.5 using MARC21slim2MODS3-5.xsl (Revision 1.106 2014/12/19)