01583     2200205   4500001002100000005001500021008004100036020001400077035001900091041000700110100002300117700002100140700001900161245013800180250002100318260002500339300003400364500084000398650013901238INLIS00000000000011120210323091301210323|||||||||   |   |||   |||| ||   |   a0852-9612  0010-0321000111  aid0 aArini Nurhandayani0 aLiliek Indrayani0 aEndang Susanto00aPerbandingan antara gejala klinik dan perubahan histopatologi untuk penilaian uji kandungan virus pada vaksin avian encephalomyelitis  aVol. 3, p. 26-28  aBogorbBBPMSOHc1990  a1 tables; 5 ref. Summary (En)  aThe purpose in this study was to compare the pathological lesion in the central nervous system in inoculated chicken by using histopathological examination with the observation of clinical sign for Avian Encephalomyelitis virus content test. Thirty-five 1-day-old SPF chicken were inoculated intracerebrally with 0.1 ml of a serial dilution: 10-2 ,10-3, and 10-4, of Avian Encephalomyelitis vaccine marketed in Indonesia and a 10-3 dilution of Japanese Avian Encephalomyelitis vaccine was used as a reference. The clinical signs were observed for three weeks postinoculation. All of the birds were exsanguinated and necropsied for histopathological examination. We concluded that the histopathological examination shows more susceptible results than the clinical signed to estimate the virus content in Avian Encephalomyelitis vaccine. 0aAnimal Diseases -- Vaccines -- CHICKENS -- DIAGNOSIS -- Specific Pathogen Free State -- Histopatology -- AVIAN ENCEPHALOMYELITIS VIRUS